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| 1788 |
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| Sir Joseph Banks founded the African Association for the furtherance of exploration and the development of trade. | 1 |
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| 1789 |
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| Smallpox epidemic broke out at Cape Coast Castle. Slaves awaiting shipment were compulsorily vaccinated. | 2 |
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| c. 1789 |
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| Catholicism introduced at Warri. | 3 |
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| 178991 |
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| Daniel Houghton explored Bambuk from the Gambia. | 4 |
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| 1792 |
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| Denmark prohibited the slave trade. | 5 |
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| 1794 |
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| French National Assembly freed all slaves without compensation (See Feb. 5). | 6 |
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| 1795 |
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| London Missionary Society (Anglican) founded. | 7 |
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| 179597 |
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| Mungo Park's first mission to the interior. Park reached Segu on the Niger River and discovered that the river flowed eastward. | 8 |
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| 1796 |
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| Wesleyan missionaries began work in Sierra Leone. | 9 |
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| 1796 |
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| Glasgow Missionary Society (Presbyterian) founded. | 10 |
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| 1799 |
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| Church Missionary Society (Anglican) founded. (See Forest West Africa) | 11 |
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